Research

The ABATE Study is testing a vaccine for Alzheimer’s disease in people with Down syndrome. The study is being conducted in collaboration with the Alzheimer's Clinical Trials Consortium – Down Syndrome - ACTC-DS.
People with Down syndrome often get Alzheimer’s disease (a type of dementia) when they get older. Dementia is a disease that causes memory loss and other thinking problems. Dementia due to Alzheimer’s occurs when a protein called amyloid builds up in the brain. About 80 people with Down syndrome will take part in the ABATE Study. The study is testing an investigational vaccine for Alzheimer’s disease in people with Down syndrome. We want to see:
• If the vaccine is safe
• How the vaccine works inside the body
• If it helps get rid of amyloid buildups
• If it slows down memory loss and thinking problems

What is a clinical research study? Clinical studies test new drugs that are not available to be prescribed yet. They test to see if the drugs are safe and effective and don’t have too many side effects. Right now, there is no treatment available for Alzheimer’s disease and dementia in people with Down syndrome. Your participation in this study could help us find a treatment. To learn more, visit Abate-study.com or contact the study team: Blake Wilson 615-936-4997 blake.wilson@vumc.org

A Research Report for Families based on findings from Treating Speech Comprehensibility in Students with Down Syndrome Study.

DSAMT is often made aware of research opportunities that are looking for participants in Middle TN. This list will give you local opportunities to make a difference in the lives of all of those with Down syndrome.

Focused on research, Medical care, Education and Advocacy.

The mission of the LuMind Foundation is to stimulate biomedical research that will accelerate the development of treatments to significantly improve cognition, including memory, learning and speech, for individuals with Down syndrome so they participate more successfully in school, lead more active and independent lives, and avoid the early onset of Alzheimer's Disease.

Training and resources for clinicians, students, researchers, and educators.